| REVIEW ARTICLE |
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| Year : 2015 | Volume
: 5
| Issue : 1 | Page : 10-14 |
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Resolvins: A novel theraputic approach in treating periodontal disease
H Nilofer Farjana, Nithya Anand, SC Chandrasekaran
Department of Periodontology, Sree Balaji Dental College and Hospital, Chennai, Tamil Nadu, India
Correspondence Address:
Dr. H Nilofer Farjana
Department of Periodontology, Sree Balaji Dental College and Hospital, Chennai, Tamil Nadu
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/2229-6360.163649
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Unresolved inflammation is associated with several widely occurring diseases such as arthritis, periodontal diseases, cancer, and atherosclerosis. Endogenous mechanisms are that which curtail excessive inflammation. A newly emerging chemical mediators derived from polyunsaturated fatty acids were identified that controls the acute inflammatory response by activating local resolution. They are specialized pro-resolving lipid mediators that includes lipoxins (LXs), resolvins (Rv), protectins, and maresins, because they are enzymatically biosynthesized during resolution of self-limited inflammation. They have anti-inflammatory and pro-resolution actions of Rv of the D1 with up regulation of arachidonic acid-derived endogenous resolution pathways (LXA4). A novel therapeutic host modulating are for resolution of inflammation. |
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