| REVIEW ARTICLE |
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| Year : 2012 | Volume
: 2
| Issue : 2 | Page : 448-451 |
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Role of genetics in patterning of face and jaws
S Kishore Kumar1, Deepak Chandrasekaran1, Faisal Tajir2, AV Vidhya Lakshmi3
1 Professor, Dept. of Orthodontics and Dentofacial Orthopedics, Sree Balaji Dental College and Hospital, Chennai, India
2 Associate Professor, Dept. of Orthodontics and Dentofacial Orthopedics, Sree Balaji Dental College and Hospital, Chennai, India
3 PG Student, Dept. of Orthodontics and Dentofacial Orthopedics, Sree Balaji Dental College and Hospital, Chennai, India
Correspondence Address:
Dr S Kishore Kumar
Professor, Dept. of Orthodontics and Dentofacial Orthopedics, Sree Balaji Dental College and Hospital, Chennai
India
 Source of Support: None, Conflict of Interest: None  | Check |
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Genetics is at present one of the most rapidly progressing fields in biology and biomedicine. The advances of gene technology have led to a rapid explosion in the understanding of the molecular mechanisms regulating embryonic development. New genes and their functions are continuously being discovered in experimental studies using animal embryos and molecular genetic studies in humans are unraveling gene mutations causing congenital defects. It is now shown in the recent year studies that the homeobox gene plays an important role in the patterning of human face and jaws. Members of the homeobox - containing genes are expressed in the cranial neural crest cell and function as transcriptional regulators that control cellular proliferation and differentiation during normal embryonic development. |
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