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REVIEW ARTICLE
Year : 2017  |  Volume : 7  |  Issue : 1  |  Page : 41-44

Pulse therapy – A newer approach


1 Department of Oral Medicine and Radiology, Government Dental College, Ballari, Karnataka, India
2 Department of Conservative, Government Dental College, Ballari, Karnataka, India

Correspondence Address:
Karuna Suran
Department of Oral Medicine and Radiology, Government Dental College Ballari, Karnataka
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijmd.ijmd_69_16

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Pulse therapy is defined as discontinuous/intermittent intravenous infusion of very high doses of corticosteroids along with certain immunosuppressive agents over a short period. It has gained its popularity since last three decades due to the advantage of minimizing the adverse effects of conventional corticosteroid therapy, and their action is supposed to be mediated through nongenomic actions within the cell. The aim of pulse therapy is to achieve a faster response and stronger efficacy and to decrease the need for long-term use of systemic corticosteroids. This paper intends to review the various available pulse therapy regimens with dosages, indications, contraindications, and adverse effects.


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