• Users Online: 234
  • Home
  • Print this page
  • Email this page
Home About us Editorial board Ahead of print Current issue Search Archives Submit article Instructions Subscribe Contacts Login 
ORIGINAL ARTICLE
Year : 2016  |  Volume : 6  |  Issue : 1  |  Page : 3-6

Evaluation of the serum antioxidant status in patients with chronic periodontitis


1 Department of Periodontics, Himachal Institute of Dental Sciences, Paonta Sahib, Himachal Pradesh, India
2 Department of Oral and Maxillofacial Pathology, HP GDC, Shimla, Himachal Pradesh, India
3 Department of Conservative Dentistry, Government Dental College, Rohtak, Haryana, India

Correspondence Address:
Parveen Dahiya
Department of Periodontics, Himachal Institute of Dental Sciences, Paonta Sahib - 170 325, Himachal Pradesh
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2229-6360.188213

Rights and Permissions

Aim: The aim of this study was to evaluate any measurable change in antioxidant and free radical scavenger status in periodontal disease. Materials and Methods: A total of forty subjects consisting of twenty test subjects and twenty controls were recruited for the study. The antioxidant defense status in serum (in terms of superoxide dismutase (SOD), glutathione peroxidase [GSHPx] and catalase [CAT]), serum lipid peroxidation (in terms of malondialdehyde), and free radical scavengers (Vitamin C) was assessed. Results: Significant differences were noted between tests and controls. Negative correlation was observed between the values of lipid peroxidation and that of SOD, GSHPx, and CAT. Our study confirmed that lowered level of SOD, CAT, and GSHPx is associated with hyper lipid peroxidation in periodontal disease. Conclusion: It is now clear that the free radicals play a critical role in the initiation and progression of periodontal disease. Furthermore, the results of the present study may have important therapeutic implications in terms of the use of the antioxidants in periodontal therapy to prevent tissue destruction.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed1605    
    Printed48    
    Emailed0    
    PDF Downloaded25    
    Comments [Add]    
    Cited by others 1    

Recommend this journal