• Users Online: 17613
  • Home
  • Print this page
  • Email this page
Home About us Editorial board Ahead of print Current issue Search Archives Submit article Instructions Subscribe Contacts Login 
CASE REPORT
Year : 2011  |  Volume : 1  |  Issue : 6  |  Page : 342-346

A large pyogenic granuloma developing into a peripheral ossifying fibroma: A case report and discussion


1 Senior Lecturer, Dept. of Oral and Maxillofacial Surgery, Thalambur, near Navalur off OMR, Chennai - 603 103, India
2 Professor and Head, Dept. of Oral and Maxillofacial Surgery, Thalambur, near Navalur off OMR, Chennai - 603 103, India

Correspondence Address:
J Muruganandhan
Dept. of Oral and Maxillofacial Surgery, Thalambur, near Navalur off OMR, Chennai - 603 103
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


Rights and PermissionsRights and Permissions

The pyogenic granuloma is a reactive vascular lesion commonly observed in the oral cavity. Local factors affecting oral hygiene predispose to its development, though systemic factors, particularly hormones, modulate its pathogenesis. Microscopically it is a vascular granulation tissue underlying an atrophic and usually ulcerated epithelium. As the lesion matures, a more fibrotic picture emerges, along with reduced vascularity. Older lesions may exhibit dystrophic calcifications, though metaplastic transformation of mesenchymal cells akin to the peripheral ossifying fibroma does occur. This results in a picture of ossifying fibroma within the lesion. There has long been speculation about the pathogenesis of the pyogenic granuloma, especially on its fate. It has been established that an irritation fibroma is clinically and histopathologically indistinguishable from a matured pyogenic granuloma. Calcifications occurring in this lesion are by no means rare, but in some cases present a diagnostic dilemma to differentiate from a peripheral ossifying fibroma. Since the latter lesion presents with a slightly different clinical behavior, it may be important to distinguish them. On the other hand, if many such cases are reported, the peripheral ossifying fibroma can be regarded as a sequela of the pyogenic granuloma, the irritation fibroma being an intermediate lesion in this continuum. We report such a case, of a large pyogenic granuloma with features of a peripheral ossifying fibroma, with a concise discussion on the pathophysiology, histopathological patterns and diagnosis.


[PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed3095    
    Printed152    
    Emailed0    
    PDF Downloaded63    
    Comments [Add]    

Recommend this journal