CASE REPORT |
|
Year : 2011 | Volume
: 1
| Issue : 6 | Page : 342-346 |
|
A large pyogenic granuloma developing into a peripheral ossifying fibroma: A case report and discussion
J Muruganandhan1, G Sivakumar2, G Sujatha1
1 Senior Lecturer, Dept. of Oral and Maxillofacial Surgery, Thalambur, near Navalur off OMR, Chennai - 603 103, India 2 Professor and Head, Dept. of Oral and Maxillofacial Surgery, Thalambur, near Navalur off OMR, Chennai - 603 103, India
Correspondence Address:
J Muruganandhan Dept. of Oral and Maxillofacial Surgery, Thalambur, near Navalur off OMR, Chennai - 603 103 India
Source of Support: None, Conflict of Interest: None | Check |
|
|
The pyogenic granuloma is a reactive vascular lesion commonly observed in the oral cavity. Local factors affecting oral hygiene predispose to its development, though systemic factors, particularly hormones, modulate its pathogenesis. Microscopically it is a vascular granulation tissue underlying an atrophic and usually ulcerated epithelium. As the lesion matures, a more fibrotic picture emerges, along with reduced vascularity. Older lesions may exhibit dystrophic calcifications, though metaplastic transformation of mesenchymal cells akin to the peripheral ossifying fibroma does occur. This results in a picture of ossifying fibroma within the lesion. There has long been speculation about the pathogenesis of the pyogenic granuloma, especially on its fate. It has been established that an irritation fibroma is clinically and histopathologically indistinguishable from a matured pyogenic granuloma. Calcifications occurring in this lesion are by no means rare, but in some cases present a diagnostic dilemma to differentiate from a peripheral ossifying fibroma. Since the latter lesion presents with a slightly different clinical behavior, it may be important to distinguish them. On the other hand, if many such cases are reported, the peripheral ossifying fibroma can be regarded as a sequela of the pyogenic granuloma, the irritation fibroma being an intermediate lesion in this continuum. We report such a case, of a large pyogenic granuloma with features of a peripheral ossifying fibroma, with a concise discussion on the pathophysiology, histopathological patterns and diagnosis. |
|
|
|
[PDF]* |
|
|
|